:root{--ink:#18274a;--body:#42495d;--accent:#6b54a4;--accent-dark:#564086;--lavender:#f3effa;--soft:#f9f7fc;--line:#e4dfec;--muted:#6b7183;--white:#fff}
/* Shared guide layouts and contextual navigation. */
.main-nav a[aria-current="page"]{color:var(--accent-dark);text-decoration:underline;text-underline-offset:8px}
.home-hero .hero h1{max-width:650px}.breadcrumb{display:flex;gap:10px;flex-wrap:wrap;font-size:11px;margin-bottom:26px;color:var(--muted)}.breadcrumb a{text-decoration:none}.guide-hero .hero-inner{grid-template-columns:minmax(0,1fr) 310px;gap:60px;padding-top:35px;padding-bottom:36px}.guide-hero h1{font-size:44px;max-width:760px}.guide-hero .intro p{font-size:17px}.guide-hero-note{border:1px solid #ddd2eb;background:#ffffffbd;border-radius:14px;padding:28px;align-self:center}.guide-hero-note>strong{display:block;font-size:27px;line-height:1.2;letter-spacing:-.7px;color:var(--ink)}.guide-hero-note>p{font-size:12px;line-height:1.9;color:var(--muted);margin:18px 0}.guide-hero-note>a{font-size:12px;font-weight:600;text-decoration:none}.guide-hero-note .section-kicker{font-size:9px;margin-bottom:20px}.guide-grid{display:grid;grid-template-columns:1fr 1fr;gap:20px;margin-top:24px}.guide-card{padding:25px;border:1px solid var(--line);border-radius:12px;background:var(--soft);text-decoration:none;display:flex;flex-direction:column;transition:border-color .15s}.guide-card:hover{border-color:var(--accent)}.article .guide-card h3{font-size:22px;margin:0 0 15px}.article .guide-card p{font-size:14px;line-height:1.75;color:var(--body);margin:0 0 20px}.guide-card>strong{display:flex;justify-content:space-between;gap:12px;font-size:12px;color:var(--accent-dark);margin-top:auto}.article .section-link{font-size:14px;font-weight:600;margin-top:22px}.section-link a{text-decoration:none}.article .cite{font-size:11px;text-decoration:none;vertical-align:super;font-weight:600}.article ul:not(.reference-list){padding-left:22px}.article li{line-height:1.75}.article li+li{margin-top:7px}.article .reference-list li,.article .prep-steps li{margin-top:0}.download-panel{display:flex;align-items:center;gap:25px;border:1px solid var(--line);border-radius:10px;padding:22px;background:var(--soft);margin:24px 0}.download-panel>div{flex:1}.download-panel strong{font-size:16px}.article .download-panel p{font-size:13px;line-height:1.7;margin-top:8px}.download-panel .btn{font-size:12px;flex:none;white-space:nowrap}.article .formula{padding:16px 20px;background:var(--lavender);border-radius:8px;font-size:15px}.answer-box,.callout{background:var(--soft);border-left:3px solid #b6a1d5;padding:21px 23px;margin:24px 0;border-radius:0 9px 9px 0}.article .answer-box p,.article .callout p{font-size:15px}.article .answer-box h3,.article .callout h3{font-size:18px;margin-top:0}
*{box-sizing:border-box}html{scroll-behavior:smooth;scroll-padding-top:105px}body{margin:0;background:var(--white);color:var(--body);font-family:Arial,Helvetica,sans-serif;-webkit-font-smoothing:antialiased}a{color:var(--accent-dark);text-decoration-thickness:1px;text-underline-offset:4px}a:focus-visible,summary:focus-visible,button:focus-visible,input:focus-visible{outline:3px solid #aa8bd3;outline-offset:4px}button,input{font:inherit}button{cursor:pointer}img{display:block}sup{font-size:10px;vertical-align:super;line-height:0;padding-left:3px}.source-marker{text-decoration:none;font-weight:700}strong{color:var(--ink)}[hidden]{display:none!important}.skip-link{position:fixed;left:16px;top:-100px;background:white;border:2px solid var(--accent);padding:12px 18px;z-index:100}.skip-link:focus{top:12px}
.site-header{height:80px;position:fixed;inset:0 0 auto;z-index:30;background:#fffffff5;border-bottom:1px solid var(--line);backdrop-filter:blur(12px)}.header-inner{max-width:1320px;height:100%;margin:auto;display:flex;align-items:center;gap:28px;justify-content:space-between}.logo{display:flex;align-items:center;gap:8px;text-decoration:none;color:var(--ink);font-weight:750;font-size:24px;letter-spacing:-.7px;white-space:nowrap}.logo-sub{font-size:12px;letter-spacing:1.8px;font-weight:600;margin-left:2px}.logo-mark{height:27px;width:27px;border:2px solid var(--accent);border-radius:9px 3px 9px 3px;position:relative;margin-right:4px}.logo-mark:after{content:'';width:11px;height:11px;border:2px solid var(--accent);border-radius:4px;position:absolute;top:5px;left:5px}.main-nav{display:flex;align-items:center;gap:23px}.main-nav a{font-size:13px;text-decoration:none;color:var(--ink);font-weight:600;white-space:nowrap}.main-nav a:hover{color:var(--accent)}.btn{display:inline-flex;align-items:center;justify-content:center;gap:14px;border:1px solid var(--ink);border-radius:7px;padding:15px 20px;line-height:1.3;font-size:14px;text-decoration:none;font-weight:650;transition:background .15s}.btn.primary{background:var(--ink);color:white}.btn.primary:hover{background:#263b68}.btn.secondary{background:white;color:var(--ink);border-color:#c8bddb}.btn.secondary:hover{background:var(--soft)}.header-cta{font-size:13px;white-space:nowrap;padding:13px 17px}.mobile-menu{display:none}.mobile-menu summary{list-style:none;cursor:pointer;font-size:25px;padding:8px}.mobile-menu summary::-webkit-details-marker{display:none}.menu-panel{position:absolute;right:20px;top:70px;min-width:230px;padding:12px;border:1px solid var(--line);border-radius:10px;background:white;box-shadow:0 10px 30px #18274a14}.menu-panel a{display:block;padding:12px;text-decoration:none;font-size:14px}
.hero{margin-top:80px;background:linear-gradient(115deg,#f9f7fd 5%,#f0ebf8 100%);border-bottom:1px solid var(--line)}.hero-inner{max-width:1220px;margin:auto;padding:64px 0 45px;display:grid;grid-template-columns:minmax(0,1fr) 420px;gap:64px;align-items:center}.eyebrow{font-size:11px;letter-spacing:2px;font-weight:700;color:var(--accent);margin-bottom:22px}.hero h1{font-size:49px;line-height:1.08;letter-spacing:-1.8px;color:var(--ink);margin:0 0 24px;font-weight:700}.hero .intro p{font-size:18px;line-height:1.65;margin:0 0 17px;max-width:630px}.hero .hero-formats{display:flex;gap:11px;flex-wrap:wrap;font-size:13px;margin-top:21px;align-items:center}.hero-formats>span{color:#a393bd}.hero-buttons{display:flex;gap:12px;margin:25px 0}.disclosure{border-top:1px solid #dad1e8;padding-top:17px;max-width:620px}.disclosure p{font-size:12px;line-height:1.6;margin:0;color:#67677d}.byline{max-width:1220px;margin:auto;padding:17px 0 20px;border-top:1px solid #e1d8ee;display:flex;gap:22px;justify-content:space-between;font-size:11px;color:#747385}
.hero-product-art{background:#ffffffc9;border:1px solid #dcd3e9;border-radius:17px;padding:24px 20px 0;overflow:hidden;box-shadow:0 12px 40px #18274a08}.visual-label{font-size:10px;letter-spacing:1.8px;color:#7c7390;font-weight:700}.hero-photos{height:294px;display:flex;align-items:center;gap:0;position:relative}.hero-vials{display:flex;width:67%;align-items:center;justify-content:center;gap:0}.packshot{position:relative;overflow:hidden;isolation:isolate;display:block;flex:none}.vial-shot{aspect-ratio:5/6;width:155px}.vial-shot img{position:absolute;max-width:none!important;max-height:none!important;height:auto!important;width:200%!important;left:-50%;top:-45%;mix-blend-mode:multiply}.hero-vials .vial-shot:first-child{width:128px;margin-top:35px}.hero-vials .vial-shot:last-child{width:143px;margin-left:-18px;margin-top:-15px}.hero-pen{width:45%;height:auto;margin-left:-17px;object-fit:contain;transform:rotate(8deg)}.art-caption{display:flex;justify-content:space-around;font-size:10px;letter-spacing:1px;font-weight:650;color:#6f6781;margin-top:-8px;padding-bottom:22px}.art-bottom{border-top:1px solid var(--line);padding:15px 0;display:flex;justify-content:space-between;gap:10px;font-size:10px;color:#747182}.art-bottom a{font-weight:650;text-decoration:none}
.article-layout{max-width:1220px;margin:0 auto;padding-top:50px;display:grid;grid-template-columns:220px minmax(0,1fr);gap:64px;align-items:start}.side-rail{position:sticky;top:106px;padding-bottom:35px;max-height:calc(100vh - 115px);overflow-y:auto;scrollbar-width:thin}.toc-label{font-size:10px;letter-spacing:1.7px;font-weight:700;color:#7e748f;margin:0 0 15px}.toc{display:flex;flex-direction:column;gap:2px}.toc a{display:flex;align-items:flex-start;gap:9px;text-decoration:none;padding:10px;font-size:12px;line-height:1.4;color:#676578;border-radius:5px}.toc-dot{flex:none;width:5px;height:5px;border-radius:50%;background:#d3c8e2;margin-top:6px}.toc a.active{background:#eee7f8;color:#59428a;font-weight:600}.toc a.active .toc-dot{background:var(--accent)}.guide-box{margin-top:25px;border-top:1px solid var(--line);padding-top:24px}.guide-box>a{display:flex;justify-content:space-between;gap:9px;border-bottom:1px solid #eee9f4;font-size:12px;text-decoration:none;padding:12px 0}.guide-box>a span{color:#a291ba}.mobile-page-toc{display:none}.article{min-width:0}.article-section{padding-bottom:44px;margin-bottom:43px;border-bottom:1px solid var(--line);scroll-margin-top:108px}.section-kicker{font-size:10px;letter-spacing:1.7px;color:#837294;font-weight:700;display:flex;gap:12px;align-items:center;margin:0 0 17px}.section-kicker>span{width:24px;height:24px;border:1px solid #d9cde9;border-radius:50%;font-size:10px;letter-spacing:0;display:flex;align-items:center;justify-content:center;background:var(--soft)}.article h2{font-size:31px;line-height:1.22;letter-spacing:-.8px;font-weight:700;color:var(--ink);margin:0 0 23px}.article h3{font-size:21px;line-height:1.3;letter-spacing:-.3px;font-weight:650;color:var(--ink);margin:27px 0 13px}.article p{font-size:17px;line-height:1.75;margin:0 0 19px}.article p:last-child{margin-bottom:0}.quick-facts{display:grid;grid-template-columns:repeat(3,1fr);gap:1px;background:var(--line);border:1px solid var(--line);border-radius:10px;overflow:hidden;margin:25px 0 0}.quick-facts>div{padding:20px;background:var(--soft)}.quick-facts strong{display:block;font-size:20px;color:var(--accent-dark);line-height:1.25;letter-spacing:-.3px}.quick-facts span{display:block;font-size:12px;line-height:1.5;color:#777084;margin-top:8px}.article .source-note{font-size:12px;line-height:1.65;color:#797184;margin-top:16px}.answer-panel{background:var(--soft);border-left:3px solid #b6a1d5;padding:21px 23px;margin:24px 0 0;border-radius:0 9px 9px 0}.article .answer-panel h3{font-size:18px;margin:0 0 10px}.article .answer-panel p{font-size:15px;line-height:1.75}
.product-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px;margin:27px 0 18px}.product-card{border:1px solid var(--line);border-radius:12px;overflow:hidden;display:flex;flex-direction:column;scroll-margin-top:110px;background:#fff}.product-shot{height:265px;display:flex;align-items:center;justify-content:center;background:linear-gradient(#faf8fd,#fff);padding:14px;border-bottom:1px solid #f0ecf5}.product-shot .vial-shot{width:180px;max-width:100%}.pen-card-image{width:100%;height:100%;max-width:250px;object-fit:contain}.product-body{padding:20px;display:flex;flex-direction:column;flex:1}.format-badge{font-size:9px;letter-spacing:.6px;color:#6b5399;background:#f0eaf8;padding:6px 8px;border-radius:4px;align-self:flex-start;display:inline-block;font-weight:700;margin-bottom:14px}.article .product-card h3{font-size:21px;margin:0 0 9px;line-height:1.25}.article .product-card p{font-size:13px;line-height:1.6;margin:0 0 15px;min-height:42px}.product-card dl{font-size:12px;margin:0 0 18px;line-height:1.5}.product-card dl>div{display:flex;justify-content:space-between;gap:8px;padding:8px 0;border-bottom:1px solid #f0ecf4}.product-card dt{color:#7b7288}.product-card dd{text-align:right;font-weight:650;color:var(--ink);margin:0;white-space:nowrap}.product-meta{font-size:11px;line-height:1.8;margin-top:auto;margin-bottom:17px;color:#82758d}.product-meta a{font-size:11px}.product-card .btn{width:100%;font-size:12px;padding:12px 9px;gap:7px}.btn[disabled]{opacity:.56;cursor:not-allowed}.btn[disabled]:hover{background:var(--ink)}
.benefit-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px;margin:25px 0}.benefit-card{border:1px solid #e4dced;border-radius:10px;background:var(--soft);padding:22px}.evidence-tag{display:block;font-size:9px;font-weight:700;line-height:1.5;letter-spacing:.75px;color:#88729f;margin-bottom:16px}.article .benefit-card h3{font-size:20px;line-height:1.3;margin:0 0 13px}.article .benefit-card p{font-size:14px;line-height:1.7}.research-strip{border:1px solid var(--line);background:#faf9fc;border-radius:10px;padding:19px 21px;display:flex;gap:14px;align-items:flex-start;margin-top:23px}.status-dot{width:8px;height:8px;border-radius:50%;background:#8d75b7;flex:none;margin-top:5px}.research-strip strong{display:block;font-size:14px}.article .research-strip p{font-size:12px;line-height:1.6;margin-top:7px}.research-strip>a{font-size:12px;white-space:nowrap;align-self:center}.table-wrap{border:1px solid #dfd5eb;border-radius:9px;overflow-x:auto;margin:25px 0;background:white;max-width:100%}.table-wrap table{width:100%;border-collapse:collapse;font-size:14px;line-height:1.6;min-width:590px}.table-wrap caption{text-align:left;padding:13px 16px;background:#fbf9fd;color:#81738d;font-size:12px;line-height:1.5}.table-wrap th,.table-wrap td{padding:15px 17px;border-top:1px solid #e9e2f0;vertical-align:top;text-align:left}.table-wrap thead th{font-size:12px;color:#594372;background:#eee7f7;font-weight:700}.table-wrap tbody th{font-size:14px;font-weight:650;color:var(--ink);width:20%}.table-wrap tbody tr:nth-child(even){background:#fcfbfd}.table-wrap td strong{white-space:nowrap}.content-split{display:grid;grid-template-columns:1fr 1fr;gap:27px;margin-top:24px}.content-split h3{margin-top:0}.article .content-split p{font-size:15px;line-height:1.75}.prep-steps{list-style:none;padding:0;margin:25px 0;counter-reset:steps}.prep-steps li{counter-increment:steps;position:relative;padding:0 0 19px 48px;margin:0 0 19px;border-bottom:1px solid #ece6f4;font-size:15px;line-height:1.75}.prep-steps li:last-child{margin-bottom:0}.prep-steps li:before{content:counter(steps);position:absolute;left:0;top:0;height:30px;width:30px;border-radius:50%;background:var(--lavender);color:var(--accent-dark);font-size:12px;font-weight:700;display:grid;place-items:center}.prep-steps strong{font-weight:700}
.calculator{margin-top:30px;border:1px solid #d8c9eb;border-radius:13px;overflow:hidden;background:#fcfaff;scroll-margin-top:105px}.calculator-top{padding:28px 28px 0}.calculator-top .section-kicker{font-size:9px;margin-bottom:14px}.article .calculator h3{font-size:25px;margin:0 0 12px}.article .calculator-top p{font-size:14px;line-height:1.65}.calculator form{padding:0 28px 25px}.calc-fields{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:15px;margin:22px 0}.calc-fields label{font-size:12px;line-height:1.6;font-weight:650;color:var(--ink);position:relative}.calc-fields label>span{font-weight:400;color:#8c7d9b;float:right}.calc-fields input{display:block;width:100%;min-width:0;border:1px solid #cfc2de;border-radius:6px;background:white;padding:12px 14px;font-size:20px;font-weight:500;color:var(--ink);margin-top:8px}.calc-fields input[aria-invalid="true"]{border-color:#a43b52}.calculator form>.btn{font-size:13px;padding:13px 18px}.preset-row{display:flex;flex-wrap:wrap;align-items:center;gap:9px;margin-top:16px;font-size:11px;color:#887c96}.preset-row button{border:1px solid #dbd0e8;background:white;color:var(--accent-dark);padding:7px 10px;border-radius:5px;font-size:11px}.preset-row button:hover{background:#eee7f6}.calc-result{padding:25px 28px;background:#eee6f8;border-top:1px solid #e0d3ec;display:grid;grid-template-columns:1fr 1fr;gap:14px}.calc-result>div>span{display:block;font-size:9px;letter-spacing:1px;color:#87709d;margin-bottom:10px}.calc-result strong{display:block;font-size:32px;font-weight:700;letter-spacing:-1px;color:#513775}.calc-result small{font-size:15px;letter-spacing:0;font-weight:500}.article .calc-result>p{font-size:12px;line-height:1.65;color:#785f91;margin:5px 0 0;grid-column:1/-1}.article .calc-footnote{padding:18px 28px 22px;font-size:11px;line-height:1.6;color:#83718e;margin:0}.article .calc-error{color:#9f2d43;background:#fff0f3;padding:20px 28px;font-size:14px;margin:0}.calculator noscript p{padding:15px 28px;font-size:12px}
.experience-list{display:grid;gap:15px;margin-top:26px}.experience-card{border:1px solid var(--line);border-radius:10px;padding:23px;background:#fcfbfe}.experience-time{display:block;font-size:10px;letter-spacing:1px;font-weight:700;color:#8a719f;margin-bottom:12px}.article .experience-card h3{font-size:21px;margin:0 0 12px}.article .experience-card p{font-size:15px;line-height:1.75}.safety-note{border:1px solid #e4dbe8;border-left:3px solid #aa92b9;padding:20px 23px;border-radius:0 8px 8px 0;background:#fbf8fc;margin-top:23px}.safety-note>strong{font-size:15px}.article .safety-note p{font-size:14px;line-height:1.7;margin-top:9px}
.coa-grid{display:grid;grid-template-columns:1fr 1fr;gap:18px;margin:26px 0}.coa-card{border:1px solid var(--line);border-radius:11px;overflow:hidden;background:#fff}.coa-preview{display:block;background:#f5f1fa;padding:20px;height:240px;overflow:hidden}.coa-preview img{width:auto;height:220px;margin:auto;box-shadow:0 5px 18px #18274a17}.coa-copy{padding:22px}.article .coa-copy h3{font-size:20px;margin:0 0 18px}.coa-value{font-size:32px;letter-spacing:-.8px;line-height:1.2;color:var(--accent-dark);font-weight:700;margin-bottom:16px}.coa-value span{display:block;font-size:11px;font-weight:400;letter-spacing:0;color:#8b7b98;margin-top:6px}.article .coa-copy p{font-size:12px;line-height:1.8;margin-bottom:18px}.coa-copy .btn{width:100%;font-size:12px;padding:12px}.faq-items details{border-top:1px solid #e8e1ef;padding:21px 0;scroll-margin-top:110px}.faq-items details:last-child{padding-bottom:0}.faq-items summary{font-size:17px;line-height:1.5;font-weight:650;color:var(--ink);cursor:pointer;list-style:none;display:flex;justify-content:space-between;align-items:flex-start;gap:20px}.faq-items summary::-webkit-details-marker{display:none}.faq-items .toggle{font-size:22px;font-weight:400;color:var(--accent);line-height:1.2}.faq-items .answer{padding:13px 30px 0 0}.article .faq-items .answer p{font-size:15px;line-height:1.75;margin:0}.article .source-intro{font-size:14px;color:#7d7186}.reference-list{list-style:none;padding:0;margin:25px 0 0;display:grid;grid-template-columns:1fr 1fr;gap:24px 26px}.reference-list li{display:flex;gap:12px;align-items:flex-start;font-size:12px;line-height:1.65;scroll-margin-top:115px}.ref-number{font-size:10px;color:#a18aae;background:#f3edf8;line-height:24px;text-align:center;height:24px;width:24px;flex:none;border-radius:4px}.reference-list a{font-weight:600;overflow-wrap:anywhere}.article .reference-list p{font-size:11px;line-height:1.6;margin:6px 0 0;color:#84788f}
.site-footer{background:#f6f3fa;border-top:1px solid var(--line);margin-top:10px;padding:44px 0 20px}.footer-inner{max-width:1220px;margin:0 auto 35px;display:grid;grid-template-columns:1.1fr 1fr 1fr 1.15fr;gap:35px}.footer-brand .logo{font-size:23px}.footer-brand p,.footer-col p{font-size:12px;line-height:1.8;color:#877c92;margin:16px 0 0}.footer-col h2{font-size:12px;line-height:1.5;margin:3px 0 17px;color:var(--ink)}.footer-col a{display:block;font-size:12px;text-decoration:none;color:#796687;line-height:1.6;margin-bottom:10px;overflow-wrap:anywhere}.footer-policy-area{max-width:1220px;margin:0 auto 25px;border-top:1px solid #e0d7ea}.footer-policy-area details{padding:13px 0;border-bottom:1px solid #e0d7ea;scroll-margin-top:100px}.footer-policy-area summary{font-size:12px;font-weight:600;color:#71617f;cursor:pointer}.footer-policy-area p{font-size:12px;line-height:1.8;color:#83758e;max-width:950px;margin:12px 0 3px}.footer-bottom{max-width:1220px;margin:auto;display:flex;justify-content:space-between;font-size:10px;line-height:1.6;color:#94869e}.footer-bottom a{text-decoration:none;color:#81708e}
@media(min-width:1600px){.header-inner{max-width:1360px}.hero-inner,.byline,.article-layout,.footer-inner,.footer-policy-area,.footer-bottom{max-width:1270px}.hero-inner{grid-template-columns:minmax(0,1fr) 440px}.hero h1{font-size:52px}}
@media(max-width:1350px){.header-inner{margin:0 30px}.hero-inner,.byline,.article-layout,.footer-inner,.footer-policy-area,.footer-bottom{margin-left:40px;margin-right:40px}.hero-inner{grid-template-columns:minmax(0,1fr) 370px;gap:42px}.hero h1{font-size:45px}.hero-vials .vial-shot:first-child{width:114px}.hero-vials .vial-shot:last-child{width:126px}.hero-photos{height:265px}.main-nav{gap:18px}.article-layout{grid-template-columns:195px minmax(0,1fr);gap:40px}.product-body{padding:17px}.product-shot{height:245px}.product-shot .vial-shot{width:160px}.article .product-card h3{font-size:19px}}
@media(max-width:1150px){.logo{font-size:22px;gap:6px}.logo-sub{font-size:10px;letter-spacing:1.3px}.logo-mark{height:24px;width:24px}.logo-mark:after{top:4px;left:4px}.main-nav{gap:14px}.main-nav a{font-size:12px}.header-inner{gap:20px}.hero-inner{grid-template-columns:minmax(0,1fr) 330px;gap:30px}.hero h1{font-size:41px}.hero .intro p{font-size:17px}.hero .hero-formats{font-size:12px;gap:8px}.hero-buttons .btn{font-size:12px;padding:13px 14px}.hero-product-art{padding:22px 16px 0}.hero-vials .vial-shot:first-child{width:99px}.hero-vials .vial-shot:last-child{width:111px}.hero-photos{height:245px}.hero-vials .vial-shot:last-child{margin-left:-12px}.art-bottom{font-size:9px}.article-layout{grid-template-columns:175px minmax(0,1fr);gap:32px}.product-grid{gap:12px}.product-body{padding:14px}.product-shot{height:220px;padding:10px}.product-shot .vial-shot{width:145px}.article .product-card h3{font-size:18px}.product-card dl{font-size:11px}.product-card dt{max-width:95px}.product-card .btn{font-size:11px}.product-card .format-badge{font-size:8px;padding:5px 6px}.benefit-grid{gap:12px}.benefit-card{padding:18px}.article .benefit-card h3{font-size:18px}.article .benefit-card p{font-size:13px}.footer-inner{gap:24px}.quick-facts>div{padding:16px}.quick-facts strong{font-size:18px}}
@media(max-width:980px){.main-nav{display:none}.mobile-menu{display:block}.header-cta{margin-left:auto}.header-inner{gap:18px}.hero-inner{grid-template-columns:minmax(0,1fr) 300px;gap:25px;padding-top:48px}.hero h1{font-size:37px}.hero .intro p{font-size:16px}.hero .hero-formats{font-size:11px;gap:6px}.hero-buttons{flex-direction:column;align-items:flex-start}.hero-buttons .btn{font-size:13px;padding:13px 17px}.hero-product-art{padding:20px 14px 0}.hero-vials .vial-shot:first-child{width:90px}.hero-vials .vial-shot:last-child{width:100px}.hero-photos{height:225px}.visual-label{font-size:9px;letter-spacing:1.4px}.art-caption{font-size:9px;letter-spacing:.5px}.art-bottom{flex-direction:column;gap:6px}.article-layout{grid-template-columns:160px minmax(0,1fr);gap:28px}.article h2{font-size:28px}.product-grid{grid-template-columns:1fr;gap:18px}.product-card{display:grid;grid-template-columns:180px minmax(0,1fr)}.product-shot{height:100%;min-height:300px;border-bottom:none;border-right:1px solid #f0ecf5}.product-shot .vial-shot{width:160px}.product-body{padding:23px}.article .product-card h3{font-size:22px}.article .product-card p{min-height:0;font-size:14px}.product-card dl{font-size:12px}.product-card dt{max-width:none}.product-card .format-badge{font-size:9px}.product-card .btn{font-size:12px}.benefit-grid{grid-template-columns:1fr}.benefit-card{padding:22px}.article .benefit-card h3{font-size:21px}.article .benefit-card p{font-size:15px}.research-strip{flex-wrap:wrap}.research-strip>div{width:calc(100% - 25px)}.research-strip>a{margin-left:22px}.quick-facts{grid-template-columns:1fr}.quick-facts>div{display:flex;justify-content:space-between;align-items:center;gap:12px;padding:17px}.quick-facts strong{font-size:18px}.quick-facts span{font-size:11px;text-align:right;margin-top:0}.coa-grid{grid-template-columns:1fr}.coa-card{display:grid;grid-template-columns:160px minmax(0,1fr)}.coa-preview{height:100%;padding:18px;display:flex;align-items:center;justify-content:center}.coa-preview img{width:100%;height:auto;max-height:260px;object-fit:contain}.coa-copy{padding:20px}.coa-copy .btn{font-size:11px}.article .coa-copy h3{font-size:18px}.coa-value{font-size:28px}.calc-fields{grid-template-columns:1fr}.calc-fields label{font-size:13px}.calc-fields input{font-size:19px}.calc-result strong{font-size:28px}.content-split{grid-template-columns:1fr;gap:20px}.reference-list{grid-template-columns:1fr}.footer-inner{grid-template-columns:1fr 1fr;gap:30px 40px}}
@media(max-width:720px){.hero-inner,.byline,.article-layout,.footer-inner,.footer-policy-area,.footer-bottom{margin-left:24px;margin-right:24px}.hero-inner{grid-template-columns:1fr;padding:40px 0 30px}.hero h1{font-size:42px;line-height:1.1;letter-spacing:-1.3px}.hero h1 br:first-child{display:none}.eyebrow{font-size:10px;margin-bottom:20px;letter-spacing:1.5px}.hero .intro p{font-size:17px}.hero .hero-formats{font-size:12px;gap:8px}.hero-buttons{flex-direction:row;align-items:stretch;gap:10px}.hero-buttons .btn{font-size:12px;padding:13px 14px;flex:1}.hero-product-art{max-width:420px;width:100%;margin:4px auto 0;padding:22px 20px 0}.hero-vials .vial-shot:first-child{width:125px}.hero-vials .vial-shot:last-child{width:138px;margin-left:-18px}.hero-photos{height:275px}.visual-label{font-size:10px}.art-caption{font-size:10px;letter-spacing:.8px}.art-bottom{flex-direction:row;font-size:10px;gap:10px}.byline{flex-direction:column;gap:8px;font-size:10px;padding:17px 0}.side-rail{display:none}.article-layout{display:block;padding-top:27px}.mobile-page-toc{display:block;border:1px solid var(--line);border-radius:8px;padding:14px 16px;margin-bottom:36px;background:var(--soft)}.mobile-page-toc summary{font-size:13px;color:var(--ink);font-weight:600;display:flex;justify-content:space-between;list-style:none;cursor:pointer}.mobile-page-toc summary::-webkit-details-marker{display:none}.mobile-page-toc .toc{padding-top:15px}.article-section{margin-bottom:36px;padding-bottom:35px}.article h2{font-size:28px;letter-spacing:-.65px}.article p{font-size:16px;line-height:1.75}.article h3{font-size:20px}.section-kicker{font-size:9px}.product-card{grid-template-columns:155px minmax(0,1fr)}.product-shot{min-height:295px}.product-shot .vial-shot{width:135px}.product-body{padding:19px}.article .product-card h3{font-size:21px}.table-wrap table{min-width:570px}.table-wrap th,.table-wrap td{padding:13px 15px}.calc-fields{grid-template-columns:repeat(3,minmax(0,1fr));gap:10px}.calc-fields label{font-size:11px}.calc-fields input{padding:11px 10px;font-size:19px}.calculator-top{padding:24px 22px 0}.calculator form{padding:0 22px 24px}.calc-result{padding:23px 22px}.article .calc-footnote{padding:17px 22px}.footer-inner{grid-template-columns:1fr 1fr}.footer-brand{grid-column:1/-1}.footer-col:last-child{grid-column:1/-1}.site-footer{padding-top:35px}}
@media(max-width:480px){.site-header{height:70px}.header-inner{margin:0 16px;gap:8px}.hero{margin-top:70px}.logo{font-size:21px;letter-spacing:-.7px}.logo-sub{font-size:8px;letter-spacing:1px}.logo-mark{display:none}.header-cta{font-size:11px;padding:10px 11px;gap:6px}.header-cta>span{display:none}.mobile-menu summary{font-size:22px;padding:8px 3px 8px 8px}.hero-inner,.byline,.article-layout,.footer-inner,.footer-policy-area,.footer-bottom{margin-left:20px;margin-right:20px}.hero h1{font-size:37px;letter-spacing:-1.1px}.hero .intro p{font-size:16px}.hero .hero-formats{font-size:11px;gap:6px}.hero-buttons .btn{padding:13px 11px;font-size:11px;gap:5px}.hero-product-art{padding:20px 16px 0}.hero-vials .vial-shot:first-child{width:102px}.hero-vials .vial-shot:last-child{width:114px;margin-left:-14px}.hero-photos{height:240px}.art-caption{font-size:9px;letter-spacing:.5px}.art-bottom{font-size:9px;gap:6px}.byline{font-size:9px}.article h2{font-size:27px}.quick-facts>div{padding:16px}.quick-facts strong{font-size:17px}.quick-facts span{max-width:160px;font-size:11px}.product-card{display:flex}.product-shot{min-height:0;height:280px;padding:18px;border-right:0;border-bottom:1px solid #f0ecf5}.product-shot .vial-shot{width:185px}.pen-card-image{max-width:285px}.product-body{padding:23px}.article .product-card h3{font-size:23px}.product-card dl{font-size:13px}.product-card .btn{padding:13px;font-size:13px}.product-meta{font-size:12px}.product-meta a{font-size:12px}.format-badge{font-size:9px}.calc-fields{grid-template-columns:1fr;gap:15px}.calc-fields label{font-size:12px}.calc-fields input{font-size:20px}.calculator form>.btn{width:100%}.calc-result{gap:12px}.calc-result strong{font-size:30px}.calc-result small{font-size:13px}.calc-result>div>span{font-size:8px;letter-spacing:.6px}.article .calculator h3{font-size:23px}.article .calculator-top p{font-size:13px}.prep-steps li{padding-left:43px;font-size:14px}.experience-card{padding:21px}.article .experience-card h3{font-size:20px}.coa-card{display:block}.coa-preview{height:240px;padding:20px}.coa-preview img{height:220px;width:auto}.coa-copy{padding:22px}.article .coa-copy h3{font-size:21px}.coa-value{font-size:32px}.coa-copy .btn{font-size:12px}.faq-items summary{font-size:16px}.faq-items .answer{padding-right:5px}.article .faq-items .answer p{font-size:14px}.footer-inner{gap:26px}.footer-brand .logo{font-size:24px}.footer-brand .logo-sub{font-size:10px}}
@media(max-width:360px){.hero h1{font-size:33px}.logo-sub{display:none}.header-cta{font-size:10px}.hero-buttons{flex-direction:column}.hero-vials .vial-shot:first-child{width:90px}.hero-vials .vial-shot:last-child{width:101px}.hero-photos{height:225px}.art-bottom{font-size:8px}.article h2{font-size:25px}.quick-facts>div{display:block}.quick-facts span{text-align:left;margin-top:6px;max-width:none}.footer-inner{grid-template-columns:1fr}.footer-col,.footer-brand{grid-column:auto!important}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}.btn{transition:none}}
@media print{.site-header,.side-rail,.mobile-page-toc,.hero-buttons,.footer-policy-area{display:none}.hero{margin-top:0}.hero-inner{padding-top:20px;grid-template-columns:1fr}.hero-product-art{display:none}.article-layout{display:block}.article-section{break-inside:auto}.product-card,.benefit-card,.table-wrap,.calculator,.coa-card{break-inside:avoid}.table-wrap{overflow:visible}.table-wrap table{min-width:0}.hero,.calc-result,.product-card{-webkit-print-color-adjust:exact;print-color-adjust:exact}.faq-items details .answer{display:block}.site-footer{padding:20px 0}.footer-inner{grid-template-columns:1fr 1fr}}

@media(max-width:1150px){.guide-hero .hero-inner{grid-template-columns:minmax(0,1fr) 260px;gap:30px}.guide-hero h1{font-size:40px}.guide-hero-note{padding:23px}.guide-hero-note>strong{font-size:25px}}
@media(max-width:980px){.guide-hero .hero-inner{grid-template-columns:1fr}.guide-hero-note{display:none}.guide-hero .hero-buttons{flex-direction:row}.guide-grid{grid-template-columns:1fr}.download-panel{display:block}.download-panel .btn{margin-top:17px}}
@media(max-width:720px){.guide-hero .hero-inner{padding-top:25px;padding-bottom:25px}.guide-hero h1{font-size:37px}.breadcrumb{font-size:10px;margin-bottom:23px}.guide-hero .intro p{font-size:16px}.guide-hero .hero-buttons{flex-wrap:wrap}.guide-hero .hero-buttons .btn{flex:auto}.guide-card{padding:23px}.article .guide-card h3{font-size:23px}}
@media(max-width:480px){.guide-hero h1{font-size:34px;letter-spacing:-1px}.guide-hero .hero-buttons{flex-direction:column}.guide-hero .hero-buttons .btn{font-size:12px}.guide-hero .eyebrow{font-size:9px}.download-panel{padding:20px}}
@media print{.guide-hero-note,.breadcrumb{display:none}.guide-hero .hero-inner{display:block}.download-panel{break-inside:avoid}}

/* Expanded research homepage */
.benefit-grid.benefit-grid-four{grid-template-columns:repeat(2,minmax(0,1fr))}.article .faq-items .answer p+p{margin-top:13px}.article #dosage-chart .table-wrap table{min-width:690px}
@media(max-width:980px){.benefit-grid.benefit-grid-four{grid-template-columns:1fr}}

/* Product navigation and commercial guide sections */
.cart-icon{width:18px;height:18px;flex:none;display:block}
.hero-commercial-points{display:flex;flex-wrap:wrap;gap:10px 20px;align-items:center;margin:0 0 20px;font-size:12px;color:var(--accent-dark)}
.hero-commercial-points>span,.hero-commercial-points>a{display:inline-flex;gap:8px;align-items:center}
.hero-commercial-points>span:before,.hero-commercial-points>a:before{content:"";width:6px;height:6px;border-radius:50%;background:var(--accent);flex:none}
.hero-commercial-points>a{text-decoration:none}
.hero-shortcuts{display:flex;flex-wrap:wrap;gap:10px 24px;margin:0 0 21px;font-size:12px;font-weight:600}
.hero-shortcuts a{text-decoration:none}
.dosage-commerce-hero .hero-inner{padding-top:35px;padding-bottom:38px}
.guide-box .rail-buy{font-weight:700;color:var(--accent-dark);background:var(--soft);padding:13px;border-radius:6px;margin-bottom:3px}
.product-callout{display:grid;grid-template-columns:minmax(0,1fr) 220px;gap:30px;align-items:center;margin:30px 0 0;padding:28px;border:1px solid var(--line);border-radius:12px;background:linear-gradient(115deg,#f9f7fd,#eee7f8)}
.article .product-callout h3{font-size:24px;margin:12px 0}
.article .product-callout p{font-size:14px;line-height:1.75;margin:0}
.product-callout-actions{display:flex;flex-direction:column;gap:10px}
.product-callout-actions .btn{font-size:12px;padding:13px 12px}
@media(max-width:980px){.product-callout{grid-template-columns:1fr;gap:20px;padding:23px}.product-callout-actions{display:grid;grid-template-columns:1fr}.hero-commercial-points{gap:10px 15px;font-size:11px}}
@media(max-width:480px){.header-cta .cart-icon{width:15px;height:15px}.commerce-hero .hero-buttons .cart-icon{width:16px;height:16px}.commerce-hero .hero-buttons{gap:9px}.commerce-hero .hero-buttons .btn{padding:13px 10px;gap:6px}.hero-shortcuts{gap:9px 18px;font-size:11px}.hero-commercial-points{font-size:10px;gap:10px 15px}.dosage-commerce-hero .hero-inner{padding-top:27px}}
@media print{.hero-shortcuts,.hero-commercial-points,.product-callout{display:none}}

/* Results, buying and safety guides */
.related-guide-links{display:flex;flex-wrap:wrap;gap:12px 22px;margin:24px 0 0;padding-top:20px;border-top:1px solid var(--line)}
.related-guide-links a{font-size:13px;font-weight:650;text-decoration:none}
.buy-commerce-hero .hero-inner{padding-top:35px;padding-bottom:38px}
.article .report-meta{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:12px 22px;margin:16px 0 0}
.report-meta div{border-top:1px solid var(--line);padding-top:12px;font-size:13px;line-height:1.65}
.report-meta dt{font-size:10px;letter-spacing:.8px;text-transform:uppercase;color:var(--muted);margin-bottom:5px}
.report-meta dd{margin:0;color:var(--ink)}
.article .safety-callout{border:1px solid #e0bac4;border-left:4px solid #a33d57;background:#fff8fa;padding:24px;border-radius:10px;margin:26px 0}
.article .safety-callout h3{margin:0 0 12px;color:#7c2940;font-size:22px}
.article .safety-callout p,.article .safety-callout li{font-size:15px;line-height:1.75}
@media(max-width:720px){.article .report-meta{grid-template-columns:1fr}.related-guide-links{flex-direction:column;gap:15px}.buy-commerce-hero .hero-inner{padding-top:27px}}

/* Dedicated publisher and document pages. */
.footer-policy-area{display:flex;gap:12px 28px;flex-wrap:wrap;padding-top:20px}.footer-policy-area>a{font-size:12px;font-weight:600;color:var(--accent-dark);text-decoration:none;scroll-margin-top:108px}.footer-policy-area>a:hover{text-decoration:underline}.support-hero .hero-inner{padding-top:32px;padding-bottom:28px}.support-hero .intro{max-width:740px}.support-hero .hero-copy{min-width:0}.support-hero h1{overflow-wrap:anywhere}.article a[href^="mailto:"]{overflow-wrap:anywhere}.menu-panel{max-height:calc(100dvh - 92px);overflow-y:auto}.coa-copy .coa-detail{font-size:12px;color:var(--muted);line-height:1.6;margin:10px 0}.article .contact-email{font-size:22px;font-weight:650;line-height:1.4;color:var(--ink);overflow-wrap:anywhere}
@media(max-width:720px){.support-hero .hero-inner{padding-top:25px;padding-bottom:25px}.footer-policy-area{gap:14px 22px}.article .contact-email{font-size:19px}}